Coil-to-α-helix transition at the Nup358-BicD2 interface activates BicD2 for dynein recruitment

Nup358, a protein of the nuclear pore complex, facilitates a nuclear positioning pathway that is essential for many biological processes, including neuromuscular and brain development. Nup358 interacts with the dynein adaptor Bicaudal D2 (BicD2), which in turn recruits the dynein machinery to positi...

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Detalles Bibliográficos
Autores principales: Gibson, James M, Cui, Heying, Ali, M Yusuf, Zhao, Xiaoxin, Debler, Erik W, Zhao, Jing, Trybus, Kathleen M, Solmaz, Sozanne R, Wang, Chunyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956292/
https://www.ncbi.nlm.nih.gov/pubmed/35229716
http://dx.doi.org/10.7554/eLife.74714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956292/
https://www.ncbi.nlm.nih.gov/pubmed/35229716
http://dx.doi.org/10.7554/eLife.74714

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