Antisense vicR-Loaded Dendritic Mesoporous Silica Nanoparticles Regulate the Biofilm Organization and Cariogenicity of Streptococcus mutans

PURPOSE: VicR is the essential response regulator related to the synthesis of exopolysaccharide (EPS) – one of the main cariogenic factors of S. mutans. An antisense vicR RNA (ASvicR) could bind to vicR mRNA, hindering the transcription and translation of the vicR gene. We had constructed a recombin...

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Detalles Bibliográficos
Autores principales: Tian, Yuting, Zhang, Yue, Zhang, Mengjiao, Chen, Xianchun, Lei, Lei, Hu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956320/
https://www.ncbi.nlm.nih.gov/pubmed/35340824
http://dx.doi.org/10.2147/IJN.S334785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956320/
https://www.ncbi.nlm.nih.gov/pubmed/35340824
http://dx.doi.org/10.2147/IJN.S334785

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