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1,25(OH)(2)D(3) Mitigates Oxidative Stress-Induced Damage to Nucleus Pulposus-Derived Mesenchymal Stem Cells through PI3K/Akt Pathway

Intervertebral disc degeneration (IVDD) is one of the main causes of low back pain. The local environment of the degenerated intervertebral disc (IVD) increases oxidative stress and apoptosis of endogenous nucleus pulposus-derived mesenchymal stem cells (NPMSCs) and weakens its ability of endogenous...

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Detalles Bibliográficos
Autores principales: Wang, Jun-wu, Zhu, Lei, Shi, Peng-zhi, Wang, Ping-chuan, Dai, Yan, Wang, Yong-xiang, Lu, Xu-hua, Cheng, Xiao-fei, Feng, Xin-min, Zhang, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956384/
https://www.ncbi.nlm.nih.gov/pubmed/35340208
http://dx.doi.org/10.1155/2022/1427110