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Paeoniflorin Upregulates Mitochondrial Thioredoxin of Schwann Cells to Improve Diabetic Peripheral Neuropathy Indicated by 4D Label-Free Quantitative Proteomics

Diabetic peripheral neuropathy (DPN) is a diabetic complication characterized by demyelination. The pathogenesis of DPN has not been fully elucidated, thus lacking therapies. In the current study, we aimed to confirm whether paeoniflorin (PF) could improve DPN by upregulating mitochondrial thioredox...

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Detalles Bibliográficos
Autores principales: Yang, Xinwei, Li, Xiao, Zhu, Yanbo, Gao, YingYing, Xu, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956397/
https://www.ncbi.nlm.nih.gov/pubmed/35340203
http://dx.doi.org/10.1155/2022/4775645