PUMILIO proteins promote colorectal cancer growth via suppressing p21

PUMILIO (PUM) proteins belong to the highly conserved PUF family post-transcriptional regulators involved in diverse biological processes. However, their function in carcinogenesis remains under-explored. Here, we report that Pum1 and Pum2 display increased expression in human colorectal cancer (CRC...

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Detalles Bibliográficos
Autores principales: Gong, Yuanyuan, Liu, Zukai, Yuan, Yihang, Yang, Zhenzhen, Zhang, Jiawei, Lu, Qin, Wang, Wei, Fang, Chao, Lin, Haifan, Liu, Sanhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956581/
https://www.ncbi.nlm.nih.gov/pubmed/35338151
http://dx.doi.org/10.1038/s41467-022-29309-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956581/
https://www.ncbi.nlm.nih.gov/pubmed/35338151
http://dx.doi.org/10.1038/s41467-022-29309-1

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