Rotating between ponatinib and imatinib temporarily increases the efficacy of imatinib as shown in a chronic myeloid leukaemia model

Targeted therapies for chronic myeloid leukaemia (CML) are effective, but rarely curative. Patients typically require treatment indefinitely, which gives ample time for drug resistance to evolve. Drug resistance issues are one of the main causes of death owing to CML, thus any means of preventing re...

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Detalles Bibliográficos
Autores principales: Lindström, H. Jonathan G., Friedman, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956613/
https://www.ncbi.nlm.nih.gov/pubmed/35338182
http://dx.doi.org/10.1038/s41598-022-09048-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956613/
https://www.ncbi.nlm.nih.gov/pubmed/35338182
http://dx.doi.org/10.1038/s41598-022-09048-5

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