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Altered intercellular communication and extracellular matrix signaling as a potential disease mechanism in human hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is considered a primary disorder of the sarcomere resulting in unexplained left ventricular hypertrophy but the paradoxical association of nonmyocyte phenotypes such as fibrosis, mitral valve anomalies and microvascular occlusion is unexplained. To understand the in...

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Detalles Bibliográficos
Autores principales: Larson, Amy, Codden, Christina J., Huggins, Gordon S., Rastegar, Hassan, Chen, Frederick Y., Maron, Barry J., Rowin, Ethan J., Maron, Martin S., Chin, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956620/
https://www.ncbi.nlm.nih.gov/pubmed/35338173
http://dx.doi.org/10.1038/s41598-022-08561-x