Disruption of 5-hydroxytryptamine 1A receptor and orexin receptor 1 heterodimer formation affects novel G protein-dependent signaling pathways and has antidepressant effects in vivo

G protein-coupled receptor (GPCR) heterodimers are new targets for the treatment of depression. Increasing evidence supports the importance of serotonergic and orexin-producing neurons in numerous physiological processes, possibly via a crucial interaction between 5-hydroxytryptamine 1A receptor (5-...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Rumin, Li, Dandan, Mao, Huiling, Wei, Xiaonan, Xu, MingDong, Zhang, Shengnan, Jiang, Yunlu, Wang, Chunmei, Xin, Qing, Chen, Xiaoyu, Li, Guorong, Ji, Bingyuan, Yan, Maocai, Cai, Xin, Dong, Bo, Randeva, Harpal S., Liu, Chuanxin, Chen, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956632/
https://www.ncbi.nlm.nih.gov/pubmed/35338110
http://dx.doi.org/10.1038/s41398-022-01886-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956632/
https://www.ncbi.nlm.nih.gov/pubmed/35338110
http://dx.doi.org/10.1038/s41398-022-01886-1

Ejemplares similares