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Safety, pharmacokinetics, and pharmacodynamics of milvexian in healthy Japanese participants

This randomized, double-blind, placebo-controlled, multiple ascending–dose study evaluated safety, tolerability, pharmacokinetics, and pharmacodynamics of multiple doses of milvexian, an oral small-molecule FXIa inhibitor, in healthy Japanese participants. Participants received oral milvexian daily...

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Detalles Bibliográficos
Autores principales: Perera, Vidya, Wang, Zhaoqing, Lubin, Susan, Ueno, Takayo, Shiozaki, Tomomi, Chen, Wei, Xu, Xiaohui, Seiffert, Dietmar, DeSouza, Mary, Murthy, Bindu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956633/
https://www.ncbi.nlm.nih.gov/pubmed/35338177
http://dx.doi.org/10.1038/s41598-022-08768-y