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Randomized clinical trial to assess the protective efficacy of a Plasmodium vivax CS synthetic vaccine

A randomized, double-blind, controlled vaccine clinical trial was conducted to assess, as the primary outcome, the safety and protective efficacy of the Plasmodium vivax circumsporozoite (CS) protein in healthy malaria-naïve (phase IIa) and semi-immune (phase IIb) volunteers. Participants (n = 35) w...

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Detalles Bibliográficos
Autores principales: Arévalo-Herrera, Myriam, Gaitán, Xiomara, Larmat-Delgado, Michelle, Caicedo, María Alejandra, Herrera, Sonia M., Henao-Giraldo, Juliana, Castellanos, Angélica, Devaud, Jean-Christophe, Pannatier, André, Oñate, José, Corradin, Giampietro, Herrera, Sócrates
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956637/
https://www.ncbi.nlm.nih.gov/pubmed/35338131
http://dx.doi.org/10.1038/s41467-022-29226-3