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Microwell bag culture for large-scale production of homogeneous islet-like clusters

Pluripotent stem-cell derived cells can be used for type I diabetes treatment, but we require at least 10(5)–10(6) islet-like clusters per patient. Although thousands of uniform cell clusters can be produced using a conventional microwell plate, numerous obstacles need to be overcome for its clinica...

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Detalles Bibliográficos
Autores principales: Suenaga, Ryo, Konagaya, Shuhei, Yamaura, Junji, Ito, Ryo, Tanaka, Satoshi, Ishizaki, Yoichi, Toyoda, Taro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956638/
https://www.ncbi.nlm.nih.gov/pubmed/35338209
http://dx.doi.org/10.1038/s41598-022-09124-w