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Microwell bag culture for large-scale production of homogeneous islet-like clusters
Pluripotent stem-cell derived cells can be used for type I diabetes treatment, but we require at least 10(5)–10(6) islet-like clusters per patient. Although thousands of uniform cell clusters can be produced using a conventional microwell plate, numerous obstacles need to be overcome for its clinica...
Autores principales: | Suenaga, Ryo, Konagaya, Shuhei, Yamaura, Junji, Ito, Ryo, Tanaka, Satoshi, Ishizaki, Yoichi, Toyoda, Taro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956638/ https://www.ncbi.nlm.nih.gov/pubmed/35338209 http://dx.doi.org/10.1038/s41598-022-09124-w |
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