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Metabolic engineering strategies to produce medium-chain oleochemicals via acyl-ACP:CoA transacylase activity

Microbial lipid metabolism is an attractive route for producing oleochemicals. The predominant strategy centers on heterologous thioesterases to synthesize desired chain-length fatty acids. To convert acids to oleochemicals (e.g., fatty alcohols, ketones), the narrowed fatty acid pool needs to be re...

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Detalles Bibliográficos
Autores principales: Yan, Qiang, Cordell, William T., Jindra, Michael A., Courtney, Dylan K., Kuckuk, Madeline K., Chen, Xuanqi, Pfleger, Brian F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956717/
https://www.ncbi.nlm.nih.gov/pubmed/35338129
http://dx.doi.org/10.1038/s41467-022-29218-3