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Metabolic engineering strategies to produce medium-chain oleochemicals via acyl-ACP:CoA transacylase activity
Microbial lipid metabolism is an attractive route for producing oleochemicals. The predominant strategy centers on heterologous thioesterases to synthesize desired chain-length fatty acids. To convert acids to oleochemicals (e.g., fatty alcohols, ketones), the narrowed fatty acid pool needs to be re...
Autores principales: | Yan, Qiang, Cordell, William T., Jindra, Michael A., Courtney, Dylan K., Kuckuk, Madeline K., Chen, Xuanqi, Pfleger, Brian F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956717/ https://www.ncbi.nlm.nih.gov/pubmed/35338129 http://dx.doi.org/10.1038/s41467-022-29218-3 |
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