Secretory quality control constrains functional selection-associated protein structure innovation

Biophysical models suggest a dominant role of structural over functional constraints in shaping protein evolution. Selection on structural constraints is linked closely to expression levels of proteins, which together with structure-associated activities determine in vivo functions of proteins. Here...

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Detalles Bibliográficos
Autores principales: Cheng, Bin, Lv, Jian-Min, Liang, Yu-Lin, Zhu, Li, Huang, Xiao-Ping, Li, Hai-Yun, Potempa, Lawrence A., Ji, Shang-Rong, Wu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956723/
https://www.ncbi.nlm.nih.gov/pubmed/35338247
http://dx.doi.org/10.1038/s42003-022-03220-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956723/
https://www.ncbi.nlm.nih.gov/pubmed/35338247
http://dx.doi.org/10.1038/s42003-022-03220-3

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