In vitro culture at 39 °C during hepatic maturation of human ES cells facilitates hepatocyte-like cell functions

Hepatocyte-like cells derived from human pluripotent stem cells (hPSC-HLCs) offer an alternative to primary hepatocytes commonly used for drug screenings and toxicological tests. However, these cells do not have hepatic functions comparable to those of hepatocytes in vivo due to insufficient hepatic...

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Detalles Bibliográficos
Autores principales: Imamura, Satoshi, Yoshimoto, Koki, Terada, Shiho, Takamuro, Kaho, Kamei, Ken-ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956733/
https://www.ncbi.nlm.nih.gov/pubmed/35338220
http://dx.doi.org/10.1038/s41598-022-09119-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956733/
https://www.ncbi.nlm.nih.gov/pubmed/35338220
http://dx.doi.org/10.1038/s41598-022-09119-7

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