Hexon modification of human adenovirus type 5 vectors enables efficient transduction of human multipotent mesenchymal stromal cells

In adenovirus type 5 (HAdV-5)-derived viral vectors, the fiber protein has been the preferred locale for modifications to alter the natural viral tropism. Hexon, the most abundant capsid protein, has rarely been used for retargeting purposes, likely because the insertion of larger targeting peptides...

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Detalles Bibliográficos
Autores principales: Nilson, Robin, Lübbers, Olivia, Schmidt, Christoph Q., Rojewski, Markus, Zeplin, Philip Helge, Funk, Wolfgang, Schrezenmeier, Hubert, Kritzinger, Astrid, Kochanek, Stefan, Krutzke, Lea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956844/
https://www.ncbi.nlm.nih.gov/pubmed/35402633
http://dx.doi.org/10.1016/j.omtm.2022.03.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956844/
https://www.ncbi.nlm.nih.gov/pubmed/35402633
http://dx.doi.org/10.1016/j.omtm.2022.03.004

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