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Icariin alleviates uveitis by targeting peroxiredoxin 3 to modulate retinal microglia M1/M2 phenotypic polarization

Uveitis causes blindness and critical visual impairment in people of all ages, and retinal microglia participate in uveitis progression. Unfortunately, effective treatment is deficient. Icariin (ICA) is a bioactive monomer derived from Epimedium. However, the role of ICA in uveitis remains elusive....

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Detalles Bibliográficos
Autores principales: Wang, Guoqing, Li, Xingran, Li, Na, Wang, Xiaotang, He, Siyuan, Li, Wanqian, Fan, Wei, Li, Ruonan, Liu, Jiangyi, Hou, Shengping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956882/
https://www.ncbi.nlm.nih.gov/pubmed/35334248
http://dx.doi.org/10.1016/j.redox.2022.102297