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Icariin alleviates uveitis by targeting peroxiredoxin 3 to modulate retinal microglia M1/M2 phenotypic polarization
Uveitis causes blindness and critical visual impairment in people of all ages, and retinal microglia participate in uveitis progression. Unfortunately, effective treatment is deficient. Icariin (ICA) is a bioactive monomer derived from Epimedium. However, the role of ICA in uveitis remains elusive....
Autores principales: | Wang, Guoqing, Li, Xingran, Li, Na, Wang, Xiaotang, He, Siyuan, Li, Wanqian, Fan, Wei, Li, Ruonan, Liu, Jiangyi, Hou, Shengping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956882/ https://www.ncbi.nlm.nih.gov/pubmed/35334248 http://dx.doi.org/10.1016/j.redox.2022.102297 |
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