Cargando…

Human tau accumulation promotes glycogen synthase kinase-3β acetylation and thus upregulates the kinase: A vicious cycle in Alzheimer neurodegeneration

BACKGROUND: Glycogen synthase kinase-3β (GSK-3β) is one of the most effective kinases in promoting tau hyperphosphorylation and accumulation in Alzheimer's disease (AD). However, it is not clear how GSK-3β activity is regulated during AD progression. METHODS: We firstly used mass spectrometry t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Qiuzhi, Li, Shihong, Li, Mengzhu, Ke, Dan, Wang, Qun, Yang, Ying, Liu, Gong-Ping, Wang, Xiao-Chuan, Liu, Enjie, Wang, Jian-Zhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956943/ https://www.ncbi.nlm.nih.gov/pubmed/35339896 http://dx.doi.org/10.1016/j.ebiom.2022.103970

Ejemplares similares

Tau‐induced upregulation of C/EBPβ‐TRPC1‐SOCE signaling aggravates tauopathies: A vicious cycle in Alzheimer neurodegeneration
por: Ye, Jinwang, et al.
Publicado: (2020)

Functional Implications of Glycogen Synthase Kinase-3-Mediated Tau Phosphorylation
por: Hanger, Diane P., et al.
Publicado: (2011)

Glycogen Synthase Kinase-3
por: Crouch, Peter, et al.
Publicado: (2011)

Possible Role of the Glycogen Synthase Kinase-3 Signaling Pathway in Trimethyltin-Induced Hippocampal Neurodegeneration in Mice
por: Kim, Juhwan, et al.
Publicado: (2013)

Tau phosphorylation by glycogen synthase kinase 3β modulates enzyme acetylcholinesterase expression
por: Cortés‐Gómez, María‐Ángeles, et al.
Publicado: (2020)

Glycogen synthase kinase 3β in tumorigenesis and oncotherapy
por: He, Rui, et al.
Publicado: (2020)

Interactomes of Glycogen Synthase Kinase-3 Isoforms
por: Cormier, Kevin W., et al.
Publicado: (2023)

Glycogen Synthase Kinase-3 Regulates Production of Amyloid-β Peptides and Tau Phosphorylation in Diabetic Rat Brain
por: Qu, Zhong-Sen, et al.
Publicado: (2014)

GSK-3β deletion in dentate gyrus excitatory neuron impairs synaptic plasticity and memory
por: Liu, Enjie, et al.
Publicado: (2017)

Association of glycogen synthase kinase-3β with Parkinson’s disease (Review)
por: LI, DA-WEI, et al.
Publicado: (2014)

Phylogenetic diversification of glycogen synthase kinase 3/SHAGGY-like kinase genes in plants
por: Yoo, Mi-Jeong, et al.
Publicado: (2006)

Identification and characterization of two wheat Glycogen Synthase Kinase 3/ SHAGGY-like kinases
por: Bittner, Thomas, et al.
Publicado: (2013)

Glycogen Synthase Kinase-3 in the Etiology and Treatment of Mood Disorders
por: Jope, Richard Scott
Publicado: (2011)

Glycogen Synthase Kinase-3 is an Intermediate Modulator of Serotonin Neurotransmission
por: Polter, Abigail M., et al.
Publicado: (2011)

Glycogen Synthase Kinase-3 Is Required for Efficient Dictyostelium Chemotaxis
por: Teo, Regina, et al.
Publicado: (2010)

The Effects of Glycogen Synthase Kinase-3beta in Serotonin Neurons
por: Zhou, Wenjun, et al.
Publicado: (2012)

Glycogen Synthase Kinase 3β in Cancer Biology and Treatment
por: Domoto, Takahiro, et al.
Publicado: (2020)

Glycogen Synthase Kinase 3: Ion Channels, Plasticity, and Diseases
por: Marosi, Mate, et al.
Publicado: (2022)

The role of glycogen synthase kinase 3 beta in neurodegenerative diseases
por: Yu, Honglu, et al.
Publicado: (2023)

Activation of GABA(B) receptors inhibits protein kinase B /Glycogen Synthase Kinase 3 signaling
por: Lu, Frances Fangjia, et al.
Publicado: (2012)

Alzheimer‐like tau accumulation in dentate gyrus mossy cells induces spatial cognitive deficits by disrupting multiple memory‐related signaling and inhibiting local neural circuit
por: Li, Shihong, et al.
Publicado: (2022)

Isoorientin Inhibits Inflammation in Macrophages and Endotoxemia Mice by Regulating Glycogen Synthase Kinase 3β
por: Li, Yingui, et al.
Publicado: (2020)

Stimulation of EphB2 attenuates tau phosphorylation through PI3K/Akt-mediated inactivation of glycogen synthase kinase-3β
por: Jiang, Jun, et al.
Publicado: (2015)

Glycogen synthase kinase 3: a crucial regulator of axotomy-induced axon regeneration
por: Liu, Jinlian, et al.
Publicado: (2019)

Antidiabetic and vasoprotective activity of lithium: Role of glycogen synthase kinase-3
por: Kanzariya, Nilesh R., et al.
Publicado: (2011)

Regulation by Glycogen Synthase Kinase-3 of Inflammation and T Cells in CNS Diseases
por: Beurel, Eléonore
Publicado: (2011)

Emerging Roles of Glycogen Synthase Kinase 3 in the Treatment of Brain Tumors
por: Mills, Caroline N., et al.
Publicado: (2011)

Aberrant glycogen synthase kinase 3β in the development of pancreatic cancer
por: Shimasaki, Takeo, et al.
Publicado: (2012)

Glycogen Synthase Kinase-3 (GSK-3)-Targeted Therapy and Imaging
por: Pandey, Mukesh K., et al.
Publicado: (2016)

Glycogen synthase kinase-3β modulation of glucocorticoid responsiveness in COPD
por: Ngkelo, Anta, et al.
Publicado: (2015)

Glycogen synthase kinase 3β in Toll-like receptor signaling
por: Ko, Ryeojin, et al.
Publicado: (2016)

Amaryllidaceae Alkaloids as Potential Glycogen Synthase Kinase-3β Inhibitors
por: Hulcová, Daniela, et al.
Publicado: (2018)

Ginsenoside Rd Attenuates Tau Phosphorylation in Olfactory Bulb, Spinal Cord, and Telencephalon by Regulating Glycogen Synthase Kinase 3β and Cyclin-Dependent Kinase 5
por: Li, Ling, et al.
Publicado: (2021)

Polarized Regulation of Glycogen Synthase Kinase-3β Is Important for Glioma Cell Invasion
por: Zou, Qifei, et al.
Publicado: (2013)

Clinicopathological and biological significance of aberrant activation of glycogen synthase kinase-3 in ovarian cancer
por: Fu, Yunfeng, et al.
Publicado: (2014)

Apoptosis of cardiomyocytes in diabetic cardiomyopathy involves overexpression of glycogen synthase kinase-3β
por: Wu, Wei, et al.
Publicado: (2019)

Control of neuronal ion channel function by glycogen synthase kinase-3: new prospective for an old kinase
por: Wildburger, Norelle C., et al.
Publicado: (2012)

Phylogeny and evolutionary history of glycogen synthase kinase 3/SHAGGY-like kinase genes in land plants
por: Qi, Xinshuai, et al.
Publicado: (2013)

Two homolog wheat Glycogen Synthase Kinase 3/SHAGGY - like kinases are involved in brassinosteroid signaling
por: Bittner, Thomas, et al.
Publicado: (2015)

Differential Roles of Glycogen Synthase Kinase 3 Subtypes Alpha and Beta in Cortical Development
por: Ma, Yan-xia, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_16r44ic6peh819hpg63nprhigv