Molecular dissection of RbpA-mediated regulation of fidaxomicin sensitivity in mycobacteria

RNA polymerase (RNAP) binding protein A (RbpA) is essential for mycobacterial viability and regulates transcription initiation by increasing the stability of the RNAP-promoter open complex (RP(o)). RbpA consists of four domains: an N-terminal tail (NTT), a core domain (CD), a basic linker, and a sig...

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Detalles Bibliográficos
Autores principales: Prusa, Jerome, Zhu, Dennis X., Flynn, Aidan J., Jensen, Drake, Ruiz Manzano, Ana, Galburt, Eric A., Stallings, Christina L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956947/
https://www.ncbi.nlm.nih.gov/pubmed/35189142
http://dx.doi.org/10.1016/j.jbc.2022.101752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956947/
https://www.ncbi.nlm.nih.gov/pubmed/35189142
http://dx.doi.org/10.1016/j.jbc.2022.101752

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