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Unbiased proteomic profiling reveals the IP3R modulator AHCYL1/IRBIT as a novel interactor of microtubule-associated protein tau

Microtubule-associated protein tau is a naturally unfolded protein that can modulate a vast array of physiological processes through direct or indirect binding with molecular partners. Aberrant tau homeostasis has been implicated in the pathogenesis of several neurodegenerative disorders, including...

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Detalles Bibliográficos
Autores principales: Wischhof, Lena, Adhikari, Aasha, Mondal, Mrityunjoy, Marsal-Cots, Anaïs, Biernat, Jacek, Mandelkow, Eva Maria, Mandelkow, Eckhard, Ehninger, Dan, Nicotera, Pierluigi, Bano, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956953/
https://www.ncbi.nlm.nih.gov/pubmed/35218773
http://dx.doi.org/10.1016/j.jbc.2022.101774