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AOP Key Event Relationship report: Linking decreased retinoic acid levels with disrupted meiosis in developing oocytes

The Adverse Outcome Pathway (AOP) concept is an emerging tool in regulatory toxicology that uses simplified descriptions to show cause-effect relationships between stressors and toxicity outcomes in intact organisms. The AOP structure is a modular framework, with Key Event Relationships (KERs) repre...

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Detalles Bibliográficos
Autores principales: Kam Draskau, Monica, Ravn Ballegaard, Anne-Sofie, Ramhøj, Louise, Bowles, Josephine, Svingen, Terje, Spiller, Cassy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957012/
https://www.ncbi.nlm.nih.gov/pubmed/35345548
http://dx.doi.org/10.1016/j.crtox.2022.100069