Subtilase cytotoxin from Shiga-toxigenic Escherichia coli impairs the inflammasome and exacerbates enteropathogenic bacterial infection

Subtilase cytotoxin (SubAB) is an AB(5) toxin mainly produced by the locus of enterocyte effacement-negative Shiga-toxigenic Escherichia coli (STEC) strain such as O113:H21, yet the contribution of SubAB to STEC infectious disease is unclear. We found that SubAB reduced activation of the STEC O113:H...

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Detalles Bibliográficos
Autores principales: Tsutsuki, Hiroyasu, Zhang, Tianli, Yahiro, Kinnosuke, Ono, Katsuhiko, Fujiwara, Yukio, Iyoda, Sunao, Wei, Fan-Yan, Monde, Kazuaki, Seto, Kazuko, Ohnishi, Makoto, Oshiumi, Hiroyuki, Akaike, Takaaki, Sawa, Tomohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957020/
https://www.ncbi.nlm.nih.gov/pubmed/35345462
http://dx.doi.org/10.1016/j.isci.2022.104050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957020/
https://www.ncbi.nlm.nih.gov/pubmed/35345462
http://dx.doi.org/10.1016/j.isci.2022.104050

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