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Loss of circadian rhythmicity in bdnf knockout zebrafish larvae

Brain-derived neurotrophic factor (BDNF) plays a pivotal role in neuronal growth and differentiation, neuronal plasticity, learning, and memory. Using CRISPR/Cas9 technology, we generated a vital Bdnf null mutant line in zebrafish and carried out its molecular and behavioral characterization. Althou...

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Detalles Bibliográficos
Autores principales: D’Agostino, Ylenia, Frigato, Elena, Noviello, Teresa M.R., Toni, Mattia, Frabetti, Flavia, Cigliano, Luisa, Ceccarelli, Michele, Sordino, Paolo, Cerulo, Luigi, Bertolucci, Cristiano, D’Aniello, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957028/
https://www.ncbi.nlm.nih.gov/pubmed/35345456
http://dx.doi.org/10.1016/j.isci.2022.104054