PharmOmics: A species- and tissue-specific drug signature database and gene-network-based drug repositioning tool

Drug development has been hampered by a high failure rate in clinical trials due to our incomplete understanding of drug functions across organs and species. Therefore, elucidating species- and tissue-specific drug functions can provide insights into therapeutic efficacy, potential adverse effects,...

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Detalles Bibliográficos
Autores principales: Chen, Yen-Wei, Diamante, Graciel, Ding, Jessica, Nghiem, Thien Xuan, Yang, Jessica, Ha, Sung-Min, Cohn, Peter, Arneson, Douglas, Blencowe, Montgomery, Garcia, Jennifer, Zaghari, Nima, Patel, Paul, Yang, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957031/
https://www.ncbi.nlm.nih.gov/pubmed/35345455
http://dx.doi.org/10.1016/j.isci.2022.104052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957031/
https://www.ncbi.nlm.nih.gov/pubmed/35345455
http://dx.doi.org/10.1016/j.isci.2022.104052

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