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Influence and interaction of resting state functional magnetic resonance and tryptophan hydroxylase-2 methylation on short-term antidepressant drug response

BACKGROUND: Most antidepressants have been developed on the basis of the monoamine deficiency hypothesis of depression, in which neuronal serotonin (5-HT) plays a key role. 5-HT biosynthesis is regulated by the rate-limiting enzyme tryptophan hydroxylase-2 (TPH2). TPH2 methylation is correlated with...

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Detalles Bibliográficos
Autores principales: Tan, Tingting, Xu, Zhi, Gao, Chenjie, Shen, Tian, Li, Lei, Chen, Zimu, Chen, Lei, Xu, Min, Chen, Bingwei, Liu, Jiacheng, Zhang, Zhijun, Yuan, Yonggui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957120/
https://www.ncbi.nlm.nih.gov/pubmed/35337298
http://dx.doi.org/10.1186/s12888-022-03860-z