Anti-angiogenic properties of rapamycin on human retinal pericytes in an in vitro model of neovascular AMD via inhibition of the mTOR pathway

PURPOSE: Choroidal neovascularizations (CNV) are partially stabilized through a coverage of pericytes leading to a partial anti-VEGF resistence. Drugs licensed for neovascular AMD (nAMD) do not take this mechanical and growth factor-driven CNV stability into account. The purpose of this work was to...

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Detalles Bibliográficos
Autores principales: Asani, Ben, Siedlecki, Jakob, Wertheimer, Christian, Liegl, Raffael, Wolf, Armin, Ohlmann, Andreas, Priglinger, Siegfried, Priglinger, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957126/
https://www.ncbi.nlm.nih.gov/pubmed/35337287
http://dx.doi.org/10.1186/s12886-022-02334-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957126/
https://www.ncbi.nlm.nih.gov/pubmed/35337287
http://dx.doi.org/10.1186/s12886-022-02334-w

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