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Physical separation of haplotypes in dikaryons allows benchmarking of phasing accuracy in Nanopore and HiFi assemblies with Hi-C data

BACKGROUND: Most animals and plants have more than one set of chromosomes and package these haplotypes into a single nucleus within each cell. In contrast, many fungal species carry multiple haploid nuclei per cell. Rust fungi are such species with two nuclei (karyons) that contain a full set of hap...

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Detalles Bibliográficos
Autores principales: Duan, Hongyu, Jones, Ashley W., Hewitt, Tim, Mackenzie, Amy, Hu, Yiheng, Sharp, Anna, Lewis, David, Mago, Rohit, Upadhyaya, Narayana M., Rathjen, John P., Stone, Eric A., Schwessinger, Benjamin, Figueroa, Melania, Dodds, Peter N., Periyannan, Sambasivam, Sperschneider, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957140/
https://www.ncbi.nlm.nih.gov/pubmed/35337367
http://dx.doi.org/10.1186/s13059-022-02658-2