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Dexmedetomidine reduces propofol-induced hippocampal neuron injury by modulating the miR-377-5p/Arc pathway

BACKGROUND: Propofol and dexmedetomidine (DEX) are widely used in general anesthesia, and exert toxic and protective effects on hippocampal neurons, respectively. The study sought to investigate the molecular mechanisms of DEX-mediated neuroprotection against propofol-induced hippocampal neuron inju...

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Detalles Bibliográficos
Autores principales:	Chen, Zong, Ding, Yong, Zeng, Ying, Zhang, Xue-Ping, Chen, Jian-Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957152/ https://www.ncbi.nlm.nih.gov/pubmed/35337381 http://dx.doi.org/10.1186/s40360-022-00555-9

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