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Omega-3 fatty acids coordinate glucose and lipid metabolism in diabetic patients
Omega 3 polyunsaturated fatty acids (n-3 PUFA) are known to have beneficial effects on cardiovascular and metabolic health. However, whether different sources of n-3 PUFA, for instance fatty fish vs vegetable oils, could elicit different effects on glucose and lipid metabolism, remains to be determi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957175/ https://www.ncbi.nlm.nih.gov/pubmed/35337345 http://dx.doi.org/10.1186/s12944-022-01642-w |
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author | Mone, Pasquale Varzideh, Fahimeh Kansakar, Urna Infante, Carmine Lombardi, Angela de Donato, Antonio Frullone, Salvatore Santulli, Gaetano |
author_facet | Mone, Pasquale Varzideh, Fahimeh Kansakar, Urna Infante, Carmine Lombardi, Angela de Donato, Antonio Frullone, Salvatore Santulli, Gaetano |
author_sort | Mone, Pasquale |
collection | PubMed |
description | Omega 3 polyunsaturated fatty acids (n-3 PUFA) are known to have beneficial effects on cardiovascular and metabolic health. However, whether different sources of n-3 PUFA, for instance fatty fish vs vegetable oils, could elicit different effects on glucose and lipid metabolism, remains to be determined. Herein we examine recent findings showing that while a plant-based n-3 PUFA supplementation for six months can reduce fasting blood glucose, marine-based n-3 PUFA can instead reduce serum levels of triglycerides. We also discuss the potential molecular mechanisms that could underlie these different effects on the regulation of glycolipid metabolism. |
format | Online Article Text |
id | pubmed-8957175 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-89571752022-03-27 Omega-3 fatty acids coordinate glucose and lipid metabolism in diabetic patients Mone, Pasquale Varzideh, Fahimeh Kansakar, Urna Infante, Carmine Lombardi, Angela de Donato, Antonio Frullone, Salvatore Santulli, Gaetano Lipids Health Dis Invited Commentary Omega 3 polyunsaturated fatty acids (n-3 PUFA) are known to have beneficial effects on cardiovascular and metabolic health. However, whether different sources of n-3 PUFA, for instance fatty fish vs vegetable oils, could elicit different effects on glucose and lipid metabolism, remains to be determined. Herein we examine recent findings showing that while a plant-based n-3 PUFA supplementation for six months can reduce fasting blood glucose, marine-based n-3 PUFA can instead reduce serum levels of triglycerides. We also discuss the potential molecular mechanisms that could underlie these different effects on the regulation of glycolipid metabolism. BioMed Central 2022-03-25 /pmc/articles/PMC8957175/ /pubmed/35337345 http://dx.doi.org/10.1186/s12944-022-01642-w Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Invited Commentary Mone, Pasquale Varzideh, Fahimeh Kansakar, Urna Infante, Carmine Lombardi, Angela de Donato, Antonio Frullone, Salvatore Santulli, Gaetano Omega-3 fatty acids coordinate glucose and lipid metabolism in diabetic patients |
title | Omega-3 fatty acids coordinate glucose and lipid metabolism in diabetic patients |
title_full | Omega-3 fatty acids coordinate glucose and lipid metabolism in diabetic patients |
title_fullStr | Omega-3 fatty acids coordinate glucose and lipid metabolism in diabetic patients |
title_full_unstemmed | Omega-3 fatty acids coordinate glucose and lipid metabolism in diabetic patients |
title_short | Omega-3 fatty acids coordinate glucose and lipid metabolism in diabetic patients |
title_sort | omega-3 fatty acids coordinate glucose and lipid metabolism in diabetic patients |
topic | Invited Commentary |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957175/ https://www.ncbi.nlm.nih.gov/pubmed/35337345 http://dx.doi.org/10.1186/s12944-022-01642-w |
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