Aberrant SKP1 Expression: Diverse Mechanisms Impacting Genome and Chromosome Stability

The S-phase Kinase-Associated Protein 1 (SKP1) is a core component of the SKP1, Cullin 1, F-box protein (SCF) complex, an E3 ubiquitin ligase that serves to poly-ubiquitinate a vast array of protein targets as a signal for their proteasomal degradation, thereby playing a critical role in the regulat...

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Detalles Bibliográficos
Autores principales: Thompson, Laura L., Rutherford, Kailee A., Lepage, Chloe C., McManus, Kirk J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957228/
https://www.ncbi.nlm.nih.gov/pubmed/35345853
http://dx.doi.org/10.3389/fcell.2022.859582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957228/
https://www.ncbi.nlm.nih.gov/pubmed/35345853
http://dx.doi.org/10.3389/fcell.2022.859582

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