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Aberrant SKP1 Expression: Diverse Mechanisms Impacting Genome and Chromosome Stability
The S-phase Kinase-Associated Protein 1 (SKP1) is a core component of the SKP1, Cullin 1, F-box protein (SCF) complex, an E3 ubiquitin ligase that serves to poly-ubiquitinate a vast array of protein targets as a signal for their proteasomal degradation, thereby playing a critical role in the regulat...
Autores principales: | Thompson, Laura L., Rutherford, Kailee A., Lepage, Chloe C., McManus, Kirk J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957228/ https://www.ncbi.nlm.nih.gov/pubmed/35345853 http://dx.doi.org/10.3389/fcell.2022.859582 |
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