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Validated LC-ESI-MS/MS method for the determination of ivosidenib in 10 μL mice plasma: application to a pharmacokinetic study

A simple, selective and rapid LC-ESI-MS/MS method has been developed and validated for the quantification of ivosidenib in mice plasma using warfarin as an internal standard (I.S.) as per regulatory guideline. Sample preparation was accomplished through a simple protein precipitation process. Chroma...

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Detalles Bibliográficos
Autores principales: Dittakavi, Sreekanth, Jat, Rakesh Kumar, Mallurwar, Sadanand Rangnathrao, Jairam, Ravi Kumar, Mullangi, Ramesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Association of Physical Chemists 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957231/
https://www.ncbi.nlm.nih.gov/pubmed/35350545
http://dx.doi.org/10.5599/admet.648