Cargando…
Quantitative structure-activity relationship to elucidate human CYP2A6 inhibition by organosulfur compounds
CYP2A6 is a human enzyme responsible for the metabolic elimination of nicotine, and it is also involved in the activation of procarcinogenic nitrosamines, especially those present in tobacco smoke. Several investigations have reported that reducing this enzyme activity may contribute to anti-smoking...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Association of Physical Chemists
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957234/ https://www.ncbi.nlm.nih.gov/pubmed/35350661 http://dx.doi.org/10.5599/admet.678 |