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PKQuest: PBPK modeling of highly lipid soluble and extracellular solutes

One of the primary objectives of physiologically based pharmacokinetics (PBPK) is the prediction of a drug’s pharmacokinetics just from knowledge of its physicochemical structure. Unfortunately, at present, the accuracy of this prediction is limited for most drugs because of uncertainty about the dr...

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Detalles Bibliográficos
Autor principal: Levitt, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Association of Physical Chemists 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957251/
https://www.ncbi.nlm.nih.gov/pubmed/35350744
http://dx.doi.org/10.5599/admet.579