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PKQuest: PBPK modeling of highly lipid soluble and extracellular solutes
One of the primary objectives of physiologically based pharmacokinetics (PBPK) is the prediction of a drug’s pharmacokinetics just from knowledge of its physicochemical structure. Unfortunately, at present, the accuracy of this prediction is limited for most drugs because of uncertainty about the dr...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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International Association of Physical Chemists
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957251/ https://www.ncbi.nlm.nih.gov/pubmed/35350744 http://dx.doi.org/10.5599/admet.579 |