CYT387, a JAK-Specific Inhibitor Impedes Osteoclast Activity and Oophorectomy-Induced Osteoporosis via Modulating RANKL and ROS Signaling Pathways

Osteoclasts are of hematopoietic lineage and have the ability to degrade mineralized bone tissues. Abnormalities in osteoclastic activity under certain pathological conditions are common in bone diseases such as osteoporosis, osteosclerosis, and arthritis. Although many kinds of drugs are currently...

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Detalles Bibliográficos
Autores principales: Li, Jing, Liang, Jiamin, Wu, Liwei, Xu, Yang, Xiao, Chengxiang, Yang, Xue, Sun, Ran, Zhao, Jinmin, Xu, Jiake, Liu, Qian, Zhou, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957263/
https://www.ncbi.nlm.nih.gov/pubmed/35345816
http://dx.doi.org/10.3389/fphar.2022.829862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957263/
https://www.ncbi.nlm.nih.gov/pubmed/35345816
http://dx.doi.org/10.3389/fphar.2022.829862

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