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Seawater fungi-derived compound screening to identify novel small molecules against dengue virus NS5 methyltransferase and NS2B/NS3 protease

Dengue fever is a virus spread by mosquitoes that has no effective treatment or vaccination. Several dengue cases combined with the current COVID-19 pandemic, exacerbates this problem. Two proteins, NS5 methyltransferase and NS2B/NS3 primary protease complexes, are crucial for dengue viral replicati...

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Detalles Bibliográficos
Autores principales: Hasan, Mahamudul, Mia, Md. Mukthar, Munna, Shahab Uddin, Talha, Md. Mowdudul Hasan, Das, Kanon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957362/
https://www.ncbi.nlm.nih.gov/pubmed/35372666
http://dx.doi.org/10.1016/j.imu.2022.100932