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Nobiletin Induces Ferroptosis in Human Skin Melanoma Cells Through the GSK3β-Mediated Keap1/Nrf2/HO-1 Signalling Pathway

Melanoma is an aggressive malignant skin tumour with an increasing global incidence. However, current treatments have limitations owing to the acquired tumour drug resistance. Ferroptosis is a recently discovered form of programmed cell death characterised by iron accumulation and lipid peroxidation...

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Detalles Bibliográficos
Autores principales: Feng, Senling, Zhou, Yongheng, Huang, Hongliang, Lin, Ying, Zeng, Yifeng, Han, Shanshan, Huang, Kaikai, Liu, Quanzhi, Zhu, Wenting, Yuan, Zhongwen, Liang, Baoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957809/
https://www.ncbi.nlm.nih.gov/pubmed/35350242
http://dx.doi.org/10.3389/fgene.2022.865073