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Novel Nongenetic Murine Model of Hyperglycemia and Hyperlipidemia-Associated Aggravated Atherosclerosis

OBJECTIVE: Atherosclerosis, the main pathology underlying cardiovascular diseases is accelerated in diabetic patients. Genetic mouse models require breeding efforts which are time-consuming and costly. Our aim was to establish a new nongenetic model of inducible metabolic risk factors that mimics hy...

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Detalles Bibliográficos
Autores principales: Gaul, Susanne, Shahzad, Khurrum, Medert, Rebekka, Gadi, Ihsan, Mäder, Christina, Schumacher, Dagmar, Wirth, Angela, Ambreen, Saira, Fatima, Sameen, Boeckel, Jes-Niels, Khawaja, Hamzah, Haas, Jan, Brune, Maik, Nawroth, Peter P., Isermann, Berend, Laufs, Ulrich, Freichel, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957812/
https://www.ncbi.nlm.nih.gov/pubmed/35350534
http://dx.doi.org/10.3389/fcvm.2022.813215