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Honokiol Inhibits HIF-1α-Mediated Glycolysis to Halt Breast Cancer Growth

Background: Hypoxia-inducible factor-1α (HIF-1α) induces the expression of glycolysis-related genes, which plays a direct and key role in Warburg effect. In a recent study, honokiol (HNK) was identified as one of the potential agents that inhibited the HIF-1α signaling pathway. Because the HIF- 1α p...

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Detalles Bibliográficos
Autores principales: Yi, Xianglan, Qi, Mengxin, Huang, Mingxiang, Zhou, Sheng, Xiong, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957822/
https://www.ncbi.nlm.nih.gov/pubmed/35350760
http://dx.doi.org/10.3389/fphar.2022.796763