Cargando…
Honokiol Inhibits HIF-1α-Mediated Glycolysis to Halt Breast Cancer Growth
Background: Hypoxia-inducible factor-1α (HIF-1α) induces the expression of glycolysis-related genes, which plays a direct and key role in Warburg effect. In a recent study, honokiol (HNK) was identified as one of the potential agents that inhibited the HIF-1α signaling pathway. Because the HIF- 1α p...
Autores principales: | Yi, Xianglan, Qi, Mengxin, Huang, Mingxiang, Zhou, Sheng, Xiong, Jing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957822/ https://www.ncbi.nlm.nih.gov/pubmed/35350760 http://dx.doi.org/10.3389/fphar.2022.796763 |
Ejemplares similares
-
Honokiol improves depression-like behaviors in rats by HIF-1α- VEGF signaling pathway activation
por: Fan, Xiao-Xu, et al.
Publicado: (2022) -
S100A6 inhibits MDM2 to suppress breast cancer growth and enhance sensitivity to chemotherapy
por: Qi, Mengxin, et al.
Publicado: (2023) -
α-Mangostin Alleviated HIF-1α-Mediated Angiogenesis in Rats With Adjuvant-Induced Arthritis by Suppressing Aerobic Glycolysis
por: Jiang, Tian-Tian, et al.
Publicado: (2021) -
Ginsenoside Compound K Regulates HIF-1α-Mediated Glycolysis Through Bclaf1 to Inhibit the Proliferation of Human Liver Cancer Cells
por: Zhang, Silin, et al.
Publicado: (2020) -
Honokiol Inhibits Atrial Metabolic Remodeling in Atrial Fibrillation Through Sirt3 Pathway
por: Liu, Guang Zhong, et al.
Publicado: (2022)