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Integrin-Linked Kinase Reduces H3K9 Trimethylation to Enhance Herpes Simplex Virus 1 Replication

Histone modifications control the lytic gene expression of herpes simplex virus 1 (HSV-1). The heterochromatin mark, trimethylation of histone H3 on lysine (K) 9 (H3K9me3), is detected on HSV-1 genomes at early phases of infection to repress viral gene transcription. However, the components and mech...

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Detalles Bibliográficos
Autores principales: Tsai, Meng-Shan, Chen, Shun-Hua, Chang, Chih-Peng, Hsiao, Yi-Ling, Wang, Li-Chiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957879/
https://www.ncbi.nlm.nih.gov/pubmed/35350437
http://dx.doi.org/10.3389/fcimb.2022.814307