Vaginal Microbiota and Mucosal Pharmacokinetics of Tenofovir in Healthy Women Using a 90-Day Tenofovir/Levonorgestrel Vaginal Ring

BACKGROUND: A relationship between the vaginal microbiota and tenofovir (TFV) concentrations and activity after topical administration has been previously reported. OBJECTIVE: CONRAD A15-138 was a randomized, placebo-controlled Phase I study aimed at characterizing the safety, pharmacokinetics (PK),...

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Detalles Bibliográficos
Autores principales: Thurman, Andrea R., Ravel, Jacques, Gajer, Pawel, Marzinke, Mark A., Ouattara, Louise A., Jacot, Terry, Peet, M. Melissa, Clark, Meredith R., Doncel, Gustavo F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957918/
https://www.ncbi.nlm.nih.gov/pubmed/35350436
http://dx.doi.org/10.3389/fcimb.2022.799501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957918/
https://www.ncbi.nlm.nih.gov/pubmed/35350436
http://dx.doi.org/10.3389/fcimb.2022.799501

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