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P2X7 Receptor Expression and Signaling on Dendritic Cells and CD4(+) T Cells is Not Required but Can Enhance Th17 Differentiation

The purinergic receptor P2X7 (P2X7R) is important in inflammasome activation and generally considered to favor proinflammatory immune responses. However, there is still a limited understanding of the role of P2X7R signaling in Th cell differentiation, particularly, Th17 differentiation. Herein, the...

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Detalles Bibliográficos
Autores principales: Yang, Yin, Story, Meaghan E., Hao, Xingxing, Sumpter, Tina L., Mathers, Alicia R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957928/
https://www.ncbi.nlm.nih.gov/pubmed/35350380
http://dx.doi.org/10.3389/fcell.2022.687659