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P2X7 Receptor Expression and Signaling on Dendritic Cells and CD4(+) T Cells is Not Required but Can Enhance Th17 Differentiation
The purinergic receptor P2X7 (P2X7R) is important in inflammasome activation and generally considered to favor proinflammatory immune responses. However, there is still a limited understanding of the role of P2X7R signaling in Th cell differentiation, particularly, Th17 differentiation. Herein, the...
Autores principales: | Yang, Yin, Story, Meaghan E., Hao, Xingxing, Sumpter, Tina L., Mathers, Alicia R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957928/ https://www.ncbi.nlm.nih.gov/pubmed/35350380 http://dx.doi.org/10.3389/fcell.2022.687659 |
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