m6A hypomethylation of DNMT3B regulated by ALKBH5 promotes intervertebral disc degeneration via E4F1 deficiency

BACKGROUND: The intervertebral disc (IVD) degeneration is the leading cause of low back pain, which accounts for a main cause of disability. N6‐methyladenosine (m6A) is the most abundant internal modification in eukaryotic messenger RNAs and is involved in various diseases and cellular processes by...

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Detalles Bibliográficos
Autores principales: Li, Gaocai, Luo, Rongjin, Zhang, Weifeng, He, Shujie, Wang, Bingjin, Liang, Huaizhen, Song, Yu, Ke, Wencan, Shi, Yunsong, Feng, Xiaobo, Zhao, Kangcheng, Wu, Xinghuo, Zhang, Yukun, Wang, Kun, Yang, Cao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957938/
https://www.ncbi.nlm.nih.gov/pubmed/35340126
http://dx.doi.org/10.1002/ctm2.765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957938/
https://www.ncbi.nlm.nih.gov/pubmed/35340126
http://dx.doi.org/10.1002/ctm2.765

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