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Regulation of Gramicidin Channel Function Solely by Changes in Lipid Intrinsic Curvature

Membrane protein function is regulated by the lipid bilayer composition. In many cases the changes in function correlate with changes in the lipid intrinsic curvature (c(0)), and c(0) is considered a determinant of protein function. Yet, water-soluble amphiphiles that cause either negative or positi...

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Detalles Bibliográficos
Autores principales: Maer, Andreia M., Rusinova, Radda, Providence, Lyndon L., Ingólfsson, Helgi I., Collingwood, Shemille A., Lundbæk, Jens A., Andersen, Olaf S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8957996/
https://www.ncbi.nlm.nih.gov/pubmed/35350699
http://dx.doi.org/10.3389/fphys.2022.836789