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Antibody-Mediated Inhibition of Insulin-Degrading Enzyme Improves Insulin Activity in a Diabetic Mouse Model

Diabetes is a metabolic disease that may lead to different life-threatening complications. While insulin constitutes a beneficial treatment, its use may be limited due to increased degradation and an increase in side effects such as weight gain and hypoglycemia. Small molecule inhibitors to insulin-...

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Detalles Bibliográficos
Autores principales: Fursht, Ofir, Liran, Mirit, Nash, Yuval, Medala, Vijay Krishna, Ini, Dor, Royal, Tabitha Grace, Goldsmith, Guy, Nahary, Limor, Benhar, Itai, Frenkel, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958001/
https://www.ncbi.nlm.nih.gov/pubmed/35350789
http://dx.doi.org/10.3389/fimmu.2022.835774