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Immune Checkpoint Inhibitor-Induced Hypophysitis and Patterns of Loss of Pituitary Function

BACKGROUND: Immune checkpoint inhibitors (ICI) are clinically active across multiple tumor types but the associated immune-related adverse events (irAEs) lead to treatment delays or discontinuation and negatively impact quality-of-life. Hypophysitis is often a permanent irAE that may affect multiple...

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Detalles Bibliográficos
Autores principales: Jessel, Shlomit, Weiss, Sarah A., Austin, Matthew, Mahajan, Amit, Etts, Katrina, Zhang, Lin, Aizenbud, Lilach, Perdigoto, Ana Luisa, Hurwitz, Michael, Sznol, Mario, Herold, Kevan C., Kluger, Harriet M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958012/
https://www.ncbi.nlm.nih.gov/pubmed/35350573
http://dx.doi.org/10.3389/fonc.2022.836859